Several studies suggest the relation of DNA methylation to diseases in humans and important phenotypes Repair Guide in plants drawing attention to this epigenetic mark as an important source of variability.In the last decades, several methodologies were developed to assess the methylation state of a genome.However, there is still a lack of affordab
BACKGROUND:Poorer cognitive ability in youth is a risk factor for later mental health problems but it is largely unknown whether cognitive ability, in youth or in later life, is predictive of mental wellbeing.The purpose of this study was to investigate whether cognitive ability at age 11 years, cognitive ability in later life, or lifetime cognitiv
Tryptophan deficiency can lead to a Assisted Opening critical shortness of niacin (vitamin B3), causing photosensitive dermatitis and a range of neurologic symptoms.The most common cause is severe protein malnutrition.However, in the case we present here, it is caused by a rare genetic disorder (Hartnup disease).A previously healthy 26-year-old wom
Ceramides (Cers) accumulate within the interstices of the outermost epidermal layers, or stratum corneum (SC), where they represent critical components of the epidermal permeability barrier.Although the SC contains substantial sphingol, indicative of ceramidase (CDase) activity, which CDase isoforms are expressed in epidermis remains unresolved.We
We present new population projections out to 2100 for Protection the countries of the European Union and for the EU as a whole under a wide range of fertility and migration scenarios.As policy-based projections rather than forecasts, they aspire not to maximize predictive success regarding future demographic developments, but to accurately show the